Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• ] constructed a fluorescent aptasensor to detect the hormone 17-estradiol in urine, water, and milk samples. They were able to detect at a limit of 0.35 nM and determined that the detection process relied on turn-on Förster resonance energy transfer. The principles of fluorescence quenching (“turn-off”) [37][38

• fluorescence quenching behaviour, and it was found that there were distinct overlaps between the analyte’s emission bands and the MOFs’ emission band at 322 nm. The FRET mechanism was therefore thought to be key in detecting these analytes. Inner filter effect (IFE): The IFE was formerly thought of as a

• over the antibiotic’s (acceptor) UV–visible spectrum. Moreover, the estimated average fluorescence lifetimes before and after the addition of tetracycline were 1.39 and 1.36 ns, respectively, and remained virtually constant. This finding strongly shows that fluorescence quenching is caused by an

A mid-infrared focusing grating coupler with a single circular arc element based on germanium on silicon

• Xiaojun Zhu,
• Shuai Li,
• Ang Sun,
• Yongquan Pan,
• Wen Liu,
• Yue Wu,
• Guoan Zhang and
• Yuechun Shi

Beilstein J. Nanotechnol. 2023, 14, 478–484, doi:10.3762/bjnano.14.38

• , transparent, and portable wrist strap sensor and a mechano-based transductive sensor in 2017 and 2018, respectively [16][17]. They have good application prospects in healthcare. In 2020, Xue et al. reported a bismuthene-enabled fluorescence quenching biosensor to detect microRNA, which is relevant to the

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• , and they were effectively used for Cu2+ detection, which was attributed to the fluorescence quenching effect of the ions [128]. A unique and quick microwave-assisted method that requires two steps was reported by Pires for the synthesis of CDs with an average size of 9 nm from an aqueous solution of a

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

• surface in order to facilitate MEF. Instead, nanostructured ZnO substrates do not show such a distance-sensitive effect, therefore, they do not induce fluorescence quenching from this point of view [112]. Even if the fluorophores are placed directly onto the ZnO nanorods surface, no quenching effect has

• the shortages of metal-based substrates, such as fabrication cost and susceptibility to fluorescence quenching. Another significant advantage of using ZnO-based substrates is their high capacity for multiplex detection, attributed to their potential to significantly enhance the fluorescence over a

• fluorescent molecules are essential. The values of quantum yield and lifetime could be influenced by non-radiative decay rates, which result from changes in the environment of the fluorophores, fluorescence quenching, or fluorescence resonance energy transfer (FRET) [112][116]. Engineered ZnO nanosubstrates

Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• solution containing plasmonic nanoparticles (from red to blue) in the presence of molecules offers an excellent tool for colorimetric sensing without the need of using advanced techniques. Similarly, selective fluorescence quenching of organic dyes or semiconducting nanoparticles by plasmonic nanoparticles

Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15

• , because of the photothermal effect, the shell shrinks thus bringing the photosensitizer closer to the core allowing for fluorescence resonance energy transfer and singlet oxygen production. In other proposed polymers, fluorescence quenching is not discussed, but in vitro studies prove the higher

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

• Sabrina Barbosa de Souza Ferreira,
• Gustavo Braga,
• Évelin Lemos Oliveira,
• Jéssica Bassi da Silva,
• Hélen Cássia Rosseto,
• Lidiane Vizioli de Castro Hoshino,
• Mauro Luciano Baesso,
• Wilker Caetano,
• Craig Murdoch,
• Helen Elizabeth Colley and
• Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

• the structuring of the micelles to promote a steric hindrance as well as higher emission intensity that promotes increased hydrophobicity of PPO blocks with higher affinity with CUR. CUR localization by fluorescence quenching The localization of CUR in the polymeric systems was performed by

• fluorescence quenching, using iodide as a hydro-soluble suppressor [2][52][53][54]. The studies were performed at 25 °C (room and administration temperature) and 37 °C (body temperature). Using this assay, it is possible to evaluate the location of CUR in the polymeric system during drug release and to

• determine the location of encapsulated drugs. If the drug is located in an external location, it forms a complex with iodide, and consequently, the intensity of the spectra decreases [52]. The fluorescence quenching studies were carried out with formulations composed of 0.02% (w/w) P407, 3.2 × 10−4% (w/w

Review of advanced sensor devices employing nanoarchitectonics concepts

• Katsuhiko Ariga,
• Tatsuyuki Makita,
• Masato Ito,
• Taizo Mori,
• Shun Watanabe and
• Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

• processes, such as catalytic reactions and fluorescence quenching, often improves sensor capabilities through component nanoarchitectonics. Imanaka and co-workers used a combustion process induced by a precious-metal-free CeO2–ZrO2–ZnO catalyst for CO gas detection [87]. The semiconducting (p-type) La2CuO4

• fluorescent gelators containing a tris(β-diketonato) complex with appropriate metals. The presence of amines can be found through fluorescence-quenching efficiencies of the thin layer films of the gel materials. The prepared films are most sensitive to the detection of tertiary amines. The discrimination and

Ceria/polymer nanocontainers for high-performance encapsulation of fluorophores

• Kartheek Katta,
• Dmitry Busko,
• Yuri Avlasevich,
• Katharina Landfester,
• Stanislav Baluschev and
• Rafael Muñoz-Espí

Beilstein J. Nanotechnol. 2019, 10, 522–530, doi:10.3762/bjnano.10.53

• , singlet oxygen is obtained through the process of fluorescence quenching [13][14][15][16]. Photooxidation significantly changes the emission properties of fluorophores because of an irreversible chemical reaction. In a simple description, the longer the fluorescence lifetime and the lower the fluorescence

• the oxygen concentration inside the capsules during polymerization. This decrease of oxygen content resulted also in a decreased rate of photodegradation of the TDI molecule. To further minimize the effect of fluorescence quenching, cerium(IV) oxide was crystallized on the surface of polymer sample NC

Electrospun one-dimensional nanostructures: a new horizon for gas sensing materials

• Muhammad Imran,
• Nunzio Motta and
• Mahnaz Shafiei

Beilstein J. Nanotechnol. 2018, 9, 2128–2170, doi:10.3762/bjnano.9.202

Luminescent supramolecular hydrogels from a tripeptide and nitrogen-doped carbon nanodots

• Maria C. Cringoli,
• Slavko Kralj,
• Marina Kurbasic,
• Massimo Urban and
• Silvia Marchesan

Beilstein J. Nanotechnol. 2017, 8, 1553–1562, doi:10.3762/bjnano.8.157

• interesting method to control fluorescence quenching upon application of a specific trigger, and to introduce new physical and optical properties of interest [7][8]. Such systems can be useful in several applications, such as bacteria detection [9], sensing of reactive oxygen species (ROS) and screening for

• drug delivery and even sensing, if the nanodots were suitably derivatized to release a drug or undergo fluorescence quenching upon binding of a specific target molecule. Results and Discussion Peptide self-assembly in the presence of NCNDs The incorporation of carbon nanostructures into hydrogels is a

Selective detection of Mg²⁺ ions via enhanced fluorescence emission using Au–DNA nanocomposites

• Tanushree Basu,
• Khyati Rana,
• Niranjan Das and
• Bonamali Pal

Beilstein J. Nanotechnol. 2017, 8, 762–771, doi:10.3762/bjnano.8.79

• the change in fluorescence quenching due to the interaction of the DNA–Ag nanocluster with Hg2+ ions in water. Also, Ma and co-workers reported the emission modulation of DNA-templated fluorescent Ag nanocomposites by divalent Mg2+ ions in 2011 [7]. Presently, there are many biosensors which are based

Synthesis of graphene–transition metal oxide hybrid nanoparticles and their application in various fields

• Arpita Jana,
• Elke Scheer and
• Sebastian Polarz

Beilstein J. Nanotechnol. 2017, 8, 688–714, doi:10.3762/bjnano.8.74

Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure

• Giovanni N. Roviello,
• Domenica Musumeci,
• Valentina Roviello,
• Marina Pirtskhalava,
• Alexander Egoyan and
• Merab Mirtskhulava

Beilstein J. Nanotechnol. 2015, 6, 1338–1347, doi:10.3762/bjnano.6.138

• “·” indicates Watson–Crick base pairing). UV and fluorescence studies showed that sanguinarine is able to bind the above-mentioned complex with a binding affinity of about 104 M−1. Fluorescence quenching and hydrodynamic studies clearly indicated the intercalation activity of sanguinarine to this RNA double

• an affinity of about 104 M−1. Furthermore, fluorescence quenching studies evidenced that berberine and palmatine act as partial intercalators of RNA double helices, while coralyne provides a complete intercalation. The interaction with these alkaloids significantly stabilises the melting of poly(rA

Tailoring the ligand shell for the control of cellular uptake and optical properties of nanocrystals

• Johannes Ostermann,
• Christian Schmidtke,
• Christopher Wolter,
• Jan-Philip Merkl,
• Hauke Kloust and
• Horst Weller

Beilstein J. Nanotechnol. 2015, 6, 232–242, doi:10.3762/bjnano.6.22

• and specificity in a broad in vitro test is demonstrated. Keywords: biolable; cellular uptake; fluorescence quenching; poylmeric micelles; quantum dots; Introduction One of the main challenges in using high quality nanoparticles for biological applications is to ensure that the ligand system

• coupled dense shell. Figure 5 shows the whole encapsulation process, including the possible cross-linking and seeded emulsion polymerization steps. A very powerful and sensitive tool to test the density of the nanocontainers is fluorescence quenching with small organic molecules or ions to simulate

• around the encapsulated nanoparticles. This can be seen from the experiments performed by Schmidtke et al. in which iron(III) ions and methylviologene were added stepwise to a solution of cross-linked and non-cross-linked QDs. Fluorescence quenching was less pronounced in the case of cross-linked

Synthesis and characterization of fluorescence-labelled silica core-shell and noble metal-decorated ceria nanoparticles

• Rudolf Herrmann,
• Markus Rennhak and
• Armin Reller

Beilstein J. Nanotechnol. 2014, 5, 2413–2423, doi:10.3762/bjnano.5.251

• investigations, noble metal NP at the surface of ceria have the ATTO 647N fluorescence label in close vicinity. One might expect electronic interactions between both which may result either in fluorescence quenching or in enhancement, depending on the distance, orientation and environment of both components [60

Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes

• Marcela Elisabeta Barbinta-Patrascu,
• Stefan Marian Iordache,
• Ana Maria Iordache,
• Nicoleta Badea and
• Camelia Ungureanu

Beilstein J. Nanotechnol. 2014, 5, 2316–2325, doi:10.3762/bjnano.5.240

• biomimetic membranes (above 41 °C) exhibits low anisotropy and high fluorescence emission intensity due to an increase in the lipid bilayer mobility and hence the chlorophyll has the possibility to move and to minimize the energy transfer leading to fluorescence quenching. In the gel phase of the artificial

• lipid bilayers (below 41 °C), high values of anisotropy and low emission fluorescence intensities of Chla inserted into lipid membranes can be observed due to the fluorescence quenching of Chla in a more rigid environment. The cholesterol-containing samples exhibited high anisotropy and the fluorophore

• their small size as compared to the samples without cholesterol (see Figure 2). This leads to fluorescence quenching due to the efficient energy transfer between chlorophyll molecules, which are closer in small vesicles. Morphological characterization of biohybrid architectures Figure 6 shows a partial

The gut wall provides an effective barrier against nanoparticle uptake

• Heike Sinnecker,
• Thorsten Krause,
• Sabine Koelling,
• Ingmar Lautenschläger and
• Andreas Frey

Beilstein J. Nanotechnol. 2014, 5, 2092–2101, doi:10.3762/bjnano.5.218

• dissolved mucus samples, we deemed the potential fluorescence-quenching effect of the reducing agent not to be substantial in our setting. In general, histological examination showed only a very small fraction of the NPs to be attached to the epithelium after removal of the mucus. Our data therefore lead us

Donor–acceptor graphene-based hybrid materials facilitating photo-induced electron-transfer reactions

• Anastasios Stergiou,
• Georgia Pagona and
• Nikos Tagmatarchis

Beilstein J. Nanotechnol. 2014, 5, 1580–1589, doi:10.3762/bjnano.5.170

• strong electronic interaction between TPP in the excited state and GO. Possible pathways for the fluorescence quenching of TPP are attributed either to an electron transfer or to an energy transfer to GO. Additionally, the formation of the charge-separated state (GO)•−–(TPP)•+ was shown to have an energy

• fluorescence quenching of the coumarin moiety. However, fluorescence is activated (on) and significantly enhanced inside the cells by glutathione-initiated dissociation. Donor–acceptor hybrids based on exfoliated graphene However, as mentioned earlier, the surface defects in the sp2-network of GO influence the

• means as well as electron microscopy. Efficient fluorescence quenching of ZnPc in the ZnPc–graphene hybrid material was observed and the deactivation pathway was evaluated by using femtosecond transient absorption spectroscopy. The charge-separated state ZnPc•+–graphene•− was identified. An electrode of

Synthesis of hydrophobic photoluminescent carbon nanodots by using L-tyrosine and citric acid through a thermal oxidation route

• Venkatesh Gude

Beilstein J. Nanotechnol. 2014, 5, 1513–1522, doi:10.3762/bjnano.5.164

• : composite materials; fluorescence quenching; hydrophobic; luminescence; upconversion; Introduction The synthesis of fluorescent functional materials raised significant interest in order to understand biological processes such as DNA sequencing, detection of DNA-hybridization, protein sensing, single

Near-field photochemical and radiation-induced chemical fabrication of nanopatterns of a self-assembled silane monolayer

• Ulrich C. Fischer,
• Carsten Hentschel,
• Florian Fontein,
• Linda Stegemann,
• Christiane Hoeppener,
• Harald Fuchs and
• Stefanie Hoeppener

Beilstein J. Nanotechnol. 2014, 5, 1441–1449, doi:10.3762/bjnano.5.156

• fluorescence quenching at sites of metal contact could not be recognized). For the processes 2 and 3, oxygen plasma and UV–ozone nanopatterning, as outlined in Figure 3a, and described in more detail in the Experimental section, the embedded mask 2 was transferred from the glass substrate onto a SAM (e.g., an

An insight into the mechanism of charge-transfer of hybrid polymer:ternary/quaternary chalcopyrite colloidal nanocrystals

• Parul Chawla,
• Son Singh and
• Shailesh Narain Sharma

Beilstein J. Nanotechnol. 2014, 5, 1235–1244, doi:10.3762/bjnano.5.137

• –Volmer quenching phenomenon, the plot of the I0/I-fluorescence intensity ratio should deliver a straight line with gradient of Ksv [14]. The resulting Stern–Volmer plot is presented in Figure 7 for the fluorescence quenching of CISe, CIGSe and CZTSe nanocrystals prepared by using a colloidal approach and

Enhancement of photocatalytic H₂ evolution of eosin Y-sensitized reduced graphene oxide through a simple photoreaction

• Weiying Zhang,
• Yuexiang Li,
• Shaoqin Peng and
• Xiang Cai

Beilstein J. Nanotechnol. 2014, 5, 801–811, doi:10.3762/bjnano.5.92

• xanthenes structure and the strong recombination of photo-excited electron–hole pairs. When GO is added to the EY solution, the fluorescence intensity of EY at 541.6 nm sharply declines to about 2.8 × 103 a.u. The addition of RGO24 results in a great fluorescence quenching of EY (Figure 4d,), the emission

Near-field effects and energy transfer in hybrid metal-oxide nanostructures

• Ulrich Herr,
• Balati Kuerbanjiang,
• Cahit Benel,
• Giorgos Papageorgiou,
• Manuel Goncalves,
• Johannes Boneberg,
• Paul Leiderer,
• Paul Ziemann,
• Peter Marek and
• Horst Hahn

Beilstein J. Nanotechnol. 2013, 4, 306–317, doi:10.3762/bjnano.4.34

• the factors influencing the experimental fluorescence measurements. Results of TiO2:Eu layers on top of Ag nanoantennas prepared in different ways are presented. To further study the effect of agglomeration and fluorescence quenching, we finally present results obtained using a nonagglomerated

Magnetic-Fe/Fe₃O₄-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

• Hongwang Wang,
• Tej B. Shrestha,
• Matthew T. Basel,
• Raj K. Dani,
• Gwi-Moon Seo,
• Sivasai Balivada,
• Marla M. Pyle,
• Heidy Prock,
• Olga B. Koper,
• Prem S. Thapa,
• David Moore,
• Ping Li,
• Viktor Chikan,
• Deryl L. Troyer and
• Stefan H. Bossmann

Beilstein J. Nanotechnol. 2012, 3, 444–455, doi:10.3762/bjnano.3.51

• (Supporting Information File 1, Figure S2). This value is close to the threshold of 30 mV, which is considered as stable for nanoparticles [51]. Fluorescence spectra of MNP-SN38 and SN38 released from the same amount of MNP-SN38 were presented in Figure 3. Significant fluorescence quenching was observed for